BDBM108945 US10017516, Compound 48::US9682983, 48

SMILES C1CC(CCN1)c1ccc(cc1)-c1cnc2c(cnn2c1)-c1ccnc2ccccc12

InChI Key InChIKey=WTMROIBZVGJXRP-UHFFFAOYSA-N

Data  12 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 108945   

TargetBone morphogenetic protein receptor type-1B(Homo sapiens (Human))
The Brigham and Women'S Hospital

US Patent
LigandPNGBDBM108945(US10017516, Compound 48 | US9682983, 48)
Affinity DataIC50:  278nMAssay Description:Compounds were assessed in ALK1-6 enzymatic assays. Specifically, compounds were assayed using LANCE® Ultra ULight technology (Perkin Elmer) against ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetBone morphogenetic protein receptor type-1B(Homo sapiens (Human))
The Brigham and Women'S Hospital

US Patent
LigandPNGBDBM108945(US10017516, Compound 48 | US9682983, 48)
Affinity DataIC50:  278nMpH: 7.5Assay Description:Specifically, compounds were assayed using LANCE® Ultra ULight¿ technology (Perkin Elmer) against human ALK1-6 enzymes (ALK1: Life Technologies, ALK2...More data for this Ligand-Target Pair
In DepthDetails US Patent